We have got one user who cant open a PDF in her browser. IE8
As far as we are aware all other users have got no issues.
iFilters for PDF is configured (Will add a post for this) and there is a icon uploaded to SharePoint.
The possible causes according to a quick search:
- Acrobat or Reader can't read the PDF file.
- The web browser isn't configured correctly with the Adobe PDF Browser plug-in.
- The web server on which the PDF file is stored can't serve the PDF file.
- You are using a 64-bit version of the Internet Explorer browser.
So i recommended that they try the 32Bit version of IE and that did the job
PS: This is apparently not needed in SharePoint 2013 anymore.. Still need to test it.